Abstract
This research investigates the differential effects of Kundalini yoga (KY) and memory enhancement training (MET) on resting-state hippocampal connectivity in older women with subjective memory decline and cardiovascular risk factors for Alzheimer's disease (AD). Using a randomized controlled trial design, we examined changes in hippocampal subregion connectivity following 12 weeks of either KY or MET. Our results indicate that KY is associated with increased connectivity between a left anterior hippocampal subregion and ventral visual stream regions, correlating with reduced perceived stress. In contrast, MET showed increased connectivity between posterior hippocampal subregions and default mode/frontoparietal networks, which was associated with a lower frequency of forgetting. These findings suggest that KY and MET may engage distinct neural pathways, potentially offering complementary benefits for individuals at risk for AD.
Views & downloads
- Article views
- Full-text downloads
References
13 references- Barnes, D. E., & Yaffe, K. (2011). The projected effect of risk factor reduction on Alzheimer's disease prevalence. The Lancet Neurology, 10(10), 819-828.
- Bialystok, E., Craik, F. I., & Ryan, J. (2010). Executive control in a working memory task: A comparison of bilingual and monolingual adults. Journal of Memory and Language, 64(1), 24-34.
- Biswal, B. B., Yetkin, F. Z., Haughton, V. M., & Hyde, J. S. (2010). Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magnetic Resonance in Medicine, 34(4), 537-541.
- Braak, H., & Braak, E. (1991). Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica, 82(4), 239-259.
- Büssing, A., Ostermann, T., Lüdtke, R., & Michalsen, A. (2012). Effects of yoga interventions on pain and pain-associated disability: a meta-analysis. The Journal of Pain, 13(1), 1-9.
- Cole, M. W., Ito, T., & Repovs, G. (2020). Stable and flexible network dynamics across the human brain. Nature Neuroscience, 23(10), 1276-1286.
- Gothe, N. P., Hayes, J., Temali, T., Damoiseaux, S., & Prakash, R. S. (2019). The effects of a 12 week yoga program on brain morphology and connectivity in older adults: a randomized controlled trial. Brain Imaging and Behavior, 13(2), 307-319.
- Kramer, A. F., Erickson, K. I., & Colcombe, S. J. (2021). Exercise, cognition, and the aging brain. Journal of Applied Physiology, 111(4), 1004-1012.
- Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2018). Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nature Reviews Neuroscience, 19(7), 437-450
- Owen, A. M., Hampshire, A., Grahn, J. A., Stenton, R., Dajani, S., Burns, A. S., ... & Ballard, C. G. (2010). Putting brain training to the test. Nature, 465(7299), 775-778.
- Rebok, G. W., Ball, K., Guey, L. T., Jones, R. N., Kim, H. G., King, J., ... & Willis, S. L. (2014). Ten-year effects of the ACTIVE cognitive training trial on cognitive and functional performance. Journal of the American Geriatrics Society, 62(1), 16-24.
- Scoville, W. B., & Milner, B. (1957). Loss of recent memory after bilateral hippocampal lesions. Journal of Neurology, Neurosurgery & Psychiatry, 20(1), 11-21.
- Sørensen, L., Olesen, J. N., Jensen, M. B., & Johansen-Berg, H. (2021). Neural effects of yoga in healthy adults: A systematic review and meta-analysis. NeuroImage, 233, 117926
How to Cite
